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Protocol for the MEXIRON study: a first-in-disease phase I–II investigation into the safety, tolerability and mechanistic proof-of-concept of extracorporeal iron depletion using the MEX-CD1 device in patients with transfusional iron overload

Auguste Dargent, Mael Heiblig, Laurent Villeneuve, Marine Alves Ferreira, Maxime Bonjour, Francois Lux, Olivier Tillement, Bernard Allaouchiche

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Source: Crossref

Published: Oct 1, 2026

DOI: 10.1136/bmjopen-2026-121216

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Protocol for the MEXIRON study: a first-in-disease phase I–II investigation into the safety, tolerability and mechanistic proof-of-concept of extracorporeal iron depletion using the MEX-CD1 device in patients with transfusional iron overload — Mathematical Frontier Network