Simulated Moving Bed Chromatography: From Concept to Proof‐of‐Concept
P. Sá Gomes, A. E. Rodrigues
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Source: Crossref
Published: Dec 2, 2011
DOI: 10.1002/ceat.201100281
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Abstract This work presents a comprehensive insight about simulated moving bed (SMB) technology, from concept to unit operation and process demonstration. A particular relevance is given to SMB nonconventional modes of operation, modeling, and design of SMB‐based separations as well as to the construction and operation of SMB units. A conventional separation of a racemic mixture of ( S , R )‐α‐tetralol by means of the FlexSMB‐LSRE® unit is addressed to better exemplify a state‐of‐the‐art SMB lab‐scale process development and demonstration.
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