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How Zn can impede Cu detoxification by chelating agents in Alzheimer's disease: a proof-of-concept study
Amandine Conte-Daban, Adam Day, Peter Faller, Christelle Hureau
Source abstract
Because zinc ions are co-localized with copper ions in the synaptic cleft, they can prevent Cu removal from the amyloid-β peptide and the resulting Cu detoxification by a chelator, unless it has a copper over zinc selectivity higher than the amyloid-β peptide.
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