Mathematical Model Analysis of Cervical Cancer Disease with Immunotheraphy
Eliya Ijtihadiyatun Fisabila, St. Budi Waluya
Source record
Source: Crossref
Published: Jun 16, 2025
DOI: 10.15294/ujm.v14i1.10717
Open original source ↗Source abstract
Cervical cancer is one type of disease that has the highest risk of death in the female population in Indonesia. Almost 95% of cervical cancer in women is caused by Human Papillomavirus (HPV) infection, which is common in women of reproductive age. In this study, a mathematical model is discussed for the case of the spread of the HPV virus to become pre-cancerous with immunotheraphy treatment. This research was conducted by building a mathematical model, analyzing the equilibrium point, and interpreting the mathematical model with numerical simulations using Maple software. This study divides the population into 5 sub-populations including susceptible (S), infected (I), precancer (P), and treatment (T) sub-populations. From the model formed, the disease-free equilibrium point and endemic equilibrium point are obtained as well as the basic reproduction number . The disease-free equilibrium point is locally asymptotically stable when and the endemic equilibrium point is locally asymptotically stable when . Based on the results of numerical simulation analysis, it is obtained that the immunotheraphy treatment is greatly affects on individual recovery.
Evidence graph
No public relationships recorded yet.
Integrity note: This page is a factual metadata record created by deterministic ingestion. It is not a claim that the work moves a mathematical frontier or has been independently verified.