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An Agentic AI Architecture for General Practitioners in Primary Care

Valentina Carbonari, Pierangelo Veltri, Pietro Hiram Guzzi

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Source: Crossref

Published: Feb 3, 2026

DOI: 10.20944/preprints202602.0164.v1

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Source abstract

Primary care physicians face increasing challenges in managing multimorbidity, continuous home-monitoring data, and fragmented access to specialty input. We propose an agentic artificial intelligence (AI) architecture for Medici di Medicina Generale (MMG) that combines a central planning large language model (LLM) with a bank of small, domain-specialized language models (SLMs) and determinis- tic tools. The system is designed for patient–home integration, safety triage, and transparent interoperability with regional infrastructures such as FSE 2.0 and ePre- scription. Here, we describe the functional schema and workflow of this architecture.

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An Agentic AI Architecture for General Practitioners in Primary Care — Mathematical Frontier Network