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Stability and Hopf bifurcation of a delayed viral infection model with logistic growth and saturated immune impairment

Jianwen Jia, Jie Li

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Source: Crossref

Published: Oct 27, 2017

DOI: 10.1002/mma.4648

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In this paper, the stability and Hopf bifurcation of a delayed viral infection model with logistic growth and saturated immune impairment is studied. It is shown that there exist 3 equilibria. The sufficient conditions for local asymptotic stability of the infection‐free equilibrium and no‐immune equilibrium are given. We also discussed the local stability of positive equilibrium and the existence of Hopf bifurcation. Moreover, the direction and stability of Hopf bifurcation is obtained by using standard form theory and the center manifold theorem. Finally, numerical simulations are performed to verify the theoretical conclusions.

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Stability and Hopf bifurcation of a delayed viral infection model with logistic growth and saturated immune impairment — Mathematical Frontier Network