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A proof-reading mechanism for non-proteinogenic amino acid incorporation into glycopeptide antibiotics

Milda Kaniusaite, Julien Tailhades, Edward A. Marschall, Robert J. A. Goode, Ralf B. Schittenhelm, Max J. Cryle

Source record

Source: Crossref

Published: Jan 1, 2019

DOI: 10.1039/c9sc03678d

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Source abstract

A complex interplay of non-ribosomal peptide synthetase domains works together with trans -acting enzymes to ensure effective GPA biosynthesis.

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A proof-reading mechanism for non-proteinogenic amino acid incorporation into glycopeptide antibiotics — Mathematical Frontier Network