FROM THE MODELING OF THE IMMUNE HALLMARKS OF CANCER TO A BLACK SWAN IN BIOLOGY
ABDELGHANI BELLOUQUID, ELENA DE ANGELIS, DAMIAN KNOPOFF
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Source: Crossref
Published: Feb 21, 2013
DOI: 10.1142/s0218202512500650
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This paper deals with the modeling of the early stage of cancer phenomena, namely mutations, onset, progression of cancer cells, and their competition with the immune system. The mathematical approach is based on the kinetic theory of active particles developed to describe the dynamics of large systems of interacting cells, called active particles. Their microscopic state is modeled by a scalar variable which expresses the main biological function. The modeling focuses on an interpretation of the immune-hallmarks of cancer.
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