differential-equations / Chemical reaction network theory: mass-action kinetics

The boundedness and persistence conjectures for weakly reversible mass-action systems

Theorem 1.1: for any finite weakly reversible network with positive constant rates and any positive x0x^0, the solution exists for all t≥0t\ge0 and some ε∈(0,1)\varepsilon\in(0,1), depending on the network, the rates and x0x^0, gives ε≤xi(t)≤ε−1\varepsilon\le x_i(t)\le\varepsilon^{-1} for all t≥0t\ge0 and all ii. The proof builds a compact convex forward-invariant polytope around each initial point from a finite concave piecewise-affine function. A remark derives convergence for complex-balanced systems, which the paper treats as known (citing Craciun's 2026 revision), not as new. The bounds are not uniform over a compatibility class (the permanence entry), and time-dependent rates are not treated.

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differential-equationsSep 25, 2026Significance 35/100Registry: lean checked

The boundedness and persistence conjectures for weakly reversible mass-action systems

Prior state unknown→proved

Theorem 1.1: for any finite weakly reversible network with positive constant rates and any positive x0x^0, the solution exists for all t≥0t\ge0 and some ε∈(0,1)\varepsilon\in(0,1), depending on the network, the rates and x0x^0, gives ε≤xi(t)≤ε−1\varepsilon\le x_i(t)\le\varepsilon^{-1} for all t≥0t\ge0 and all ii. The proof builds a compact convex forward-invariant polytope around each initial point from a finite concave piecewise-…

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Theorem 1.1: for any finite weakly reversible network with positive constant rates and any positive x0x^0, the solution exists for all t≥0t\ge0 and some ε∈(0,1)\varepsilon\in(0,1), depending on the network, the rates and x0x^0, gives ε≤xi(t)≤ε−1\varepsilon\le x_i(t)\le\varepsilon^{-1} for all t≥0t\ge0 and all ii. The proof builds a compact convex forward-invariant polytope around each initial point from a finite concave piecewise-affine function. A remark derives convergence for complex-balanced systems, which the paper treats as known (citing Craciun's 2026 revision), not as new. The bounds are not uniform over a compatibility class (the permanence entry), and time-dependent rates are not treated.

Theorem 1.1: for any finite weakly reversible network with positive constant rates and any positive x0x^0, the solution exists for all t≥0t\ge0 and some ε∈(0,1)\varepsilon\in(0,1), depending on the network, the rates and x0x^0, gives ε≤xi(t)≤ε−1\varepsilon\le x_i(t)\le\varepsilon^{-1} for all t≥0t\ge0 and all ii. The proof builds a compact convex forward-invariant polytope around each initial point from a finite concave piecewise-affine function. A remark derives convergence for complex-balanced systems, which the paper treats as known (citing Craciun's 2026 revision), not as new. The bounds are not uniform over a compatibility class (the permanence entry), and time-dependent rates are not treated.

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